Figure 3.
Overview of somatic mutations identified in the pediatric sporadic BL cohort. Mutations affecting genes previously identified as commonly mutated in BL are shown. Each column represents a BL sample, ordered by the presence or absence of FOXO1 mutations. EBV status is indicated as positive or negative. Mutations are colored-coded by type. The prevalence of different mutations in FOXO1 mutated (blue) and nonmutated (orange) cases is shown in the right-hand barcharts and genes significantly more commonly mutated in FOXO1 mutated cases are indicated by an asterisk (Fisher’s exact test). EBV, Epstein-Barr virus; Fs, frameshift.