Study design. SoC treatment included 1.0 mg/kg corticosteroids daily (prednisone or equivalent) and CsA or Tac at the usually prescribed dose to maintain the appropriate institutional practice serum level. Corticosteroid doses were tapered to 0.5 mg/kg per day by week (Wk) 8 (±1 week), 0.25 mg/kg per day by week 16 (±1 week), and 0.125 mg/kg per day by week 24 (±1 week); this dose was maintained until week 28. CsA, cyclosporine A; FFS, failure-free survival; LTFU, long-term follow-up; ORR, overall response rate; Tac, tacrolimus; TSS, total skin score; Tx, treatment.