Figure 5.
Features of an LCDD. Glomerulus with nodular mesangial expansion (arrowheads; original magnification ×400; PAS; upper left panel). IF showed strong positivity for κ light chain (upper right panel); compare with negative λ (lower left panel) in glomerular and tubular basement membranes and mesangial nodules, in keeping with a κ LCDD (original magnification ×200; fluorescein isothiocyanate). TE microscopy image shows powdery electron-dense deposits along basement membranes (arrowheads) in keeping with LCDD (original magnification ×6000, fluorescein isothiocyanate; lower right panel).