Elevated expression of cell cycle- and proliferation-associated genes is associated with poor event-free survival (EFS) (left) and overall survival (OS) (right).

Kaplan-Meier curves based on the four quartiles of CCNB1 (top), PCNA (middle), and BUB1B (bottom) gene expression. Q1 is the lowest quartile and Q4 is the highest. Note that all Q4 patients tend to do poorly.