Figure 1.
Domain structure of the plasma VWF-cleaving metalloprotease, ADAMTS13.
Abbreviations: MP, metalloprotease (proteolytic) domain; TSP, thrombospondin-1-like domain (a total of 8 are present); CUB, two similar domains containing peptide sequences found in the complement components, C1r/C1s, a sea urchin protein, and a bone morphogenic protein.