A model for predicting the outcome of sinusoidal obstruction syndrome (SOS) among patients conditioned with cyclophosphamide-based regimens.

The contour lines estimate the probability of developing severe SOS as ≥ 30%, ≥ 40%, ≥ 50%, and ≥ 60%, using total serum bilirubin in mg/dL and percentage weight gain above baseline from day −1 through day +16. If a plotted point lies above a given probability line, the probability of severe SOS is or exceeds the percentage of that line.

Reprinted with permission from the