Treatment results in precursor B cell acute lymphoblastic leukemia (p-Bc-ALL) and T cell ALL by early response (ALL-BFM 86 and 90).
A: 10y-probability for event-free survival (pEFS) in p-Bc ALL with < 1,000 leukemic cells at day 8 (prednisone good response)
Log-rank: P < 0.01 for all comparisons, except for: 6–9y vs 15–18y: P = 0.04; < 1y vs. 10–14y or 15–18y, 10–14y vs 15–18y: P = n.s.
B: 10y-pEFS in p-Bc ALL with ≥ 1,000 leukemic cells at day 8 (prednisone poor response)
Log-rank: P < 0.01 for all comparisons, except for: < 1y vs 6–9y: P = 0.02; < 1 vs. 10–14y: P = 0.04; < 1y vs 15–18y, 6–9y vs 10–14y, 6–9y vs 15–18y, and 10–14y vs 15–18y: P = n.s.
C: 10y-pEFS in T-cell ALL with < 1,000 leukemic cells at day 8 (prednisone good response)
Log-rank: P = n.s.
D: 10y-pEFS in T-cell ALL with ≥ 1,000 leukemic cells at day 8 (prednisone poor response)
Log-rank: P = n.s.