Morphology and DNA content of megakaryocytic cells overexpressing AML/EVI1. (A) Electron micrographs of megakaryocytes in E13.5 fetal liver. N indicates nucleus; dms, demarcation membrane (OM, × 3000). (B) Expression of AML1/EVI1 chimeric protein in transfected K562 cells. An arrow indicates overexpressed AML1/EVI1 proteins. (C) Electron micrographs of mock or AML1/EVI1-overexpressing K562 cells after staurosporine treatment for 48 hours. N indicates nucleus; dms, demarcation membrane (OM, × 3000). (D) DNA content of mock or AML1/EVI1-overexpressing K562 cells after staurosporine treatment for 48 hours.