Figure 5.
Morphology of serially replated AML1/EVI1/+hematopoietic colonies. (Left) WT and typical dysplastic multilineage AML1/EVI1/+ colonies after the fourth passage. The size of AML1/EVI1/+ hematopoietic colonies is significantly larger than that of WT colonies. (Right) Wright-Giemsa-stained cytocentrifuge preparations of the WT and AML1/EVI1/+ colony. AML1/EVI1/+ hematopoietic colonies maintain the dysplastic nature. Scales bars equal 300 μm (OL, 100 ×/1.40; OM, × 1000).