Figure 5.
Recipients of kidney transplants have lower frequencies of IL-7Rα+cells. (A) Two graphs in which the percentages of IL-7Rα+ cells are plotted within total CD8+ T cells (left graph) or within CMV-specific CD8+ T cells (right graph) in healthy persons and in recipients of kidney transplants. Horizontal lines indicate the median values. (B) Relation between IL-7Rα expression on CMV-specific CD8+ T cells in recipients of kidney transplants (measured more than 1 year after transplantation) and the peak viral load measured since transplantation in copies per milliliter whole blood. (C) Dot plots of CFSE compared with IL-7Rα expression from isolated IL-7Rα+ CMV-specific CD8+ T cells, cultured for 6 days.