Figure 6.
Antiviral cytokine gene expression profile of SARS-CoV–infected human immature DCs by quantitative RT-PCR. Antiviral cytokine mRNA concentrations in adult (A) and CB (B) immature cells were assayed at 3 hours and 9 hours after infection with SARS-CoV (MOI = 1). Mock-infected cells were included as negative control. The concentrations were normalized to those of β-actin mRNA in the corresponding sample. There were low expressions of IFN-α, IFN-β, IFN-γ, and IL-12p40 genes in SARS-CoV–infected DCs. Data are shown as mean ± SEM (adult n = 7; CB n = 5).