Figure 5.
Immunomonitoring shows local and syngeneic changes during therapy. (A) Levels of IFN-γ, CD4, and CD8 mRNA as detected by RT-PCR in biopsies at baseline in comparison with posttreatment biopsies. (B) Kinetics of IL-2, IFN-γ, and IL-12 serum levels and CD4/CD8 ratio. (C) Antibody titers of individual anti-measles IgG antibodies before and after therapy as measured by ELISA. Values presented as indexes (Index = OD optical density value/cut-off). Error bars indicate standard deviation.