DHMEQ can rescue SCID mice inoculated with MT-2 cells. (A) Survival curves of the SCID mice injected with MT-2 cells. DHMEQ was used at a dose of 4 mg or 12 mg/kg body weight. The differences are statistically significant (both P < .05 by Cox-Mantel test). (B) Reduction of MT-2 cells in the peritoneal mass after DHMEQ treatment. MT-2 cells were detected by immunohistochemistry using anti-p19 antibody. Original magnification ×100. Objective lens, 10×/0.4. (C) Effects of DHMEQ on MT-2 cells. DHMEQ cytotoxicity on MT-2 cells. Cells were treated with 10 μg/mL DHMEQ for 48 hours, and viabilities were studied by MTT assay. K562 cells were used as a control. Data represent the mean ± SD of 3 independent experiments. M indicates MT-2; K, K562.