Elimination of HIV-1-infected MDMs from brains of 1-MT-treated hu-PBL-NOD/SCID HIVE mice. 1-MT-treated mice (B) contained fewer HIV-1 p24⁺ MDMs as compared with controls (A). HIV-1 p24⁺ cells were counted in brain tissue sections of control (C) and 1-MT-treated (D) at weeks 2 and 3 after intracerebral inoculation of HIV-1-infected MDMs. ^*P < .05 (1-MT versus vehicle control). Original magnification for panels A and B: × 10 (insets: × 200). Error bars indicate SEM.