Increased numbers of B cells in Bcl-2 transgenic Vav-deficient mice. Scatter plots show the absolute numbers of B, T1, T2, T3, mature FO, and MZ B cells based on the data presented in Figure 5. Mice genotypes are represented as follows: wild-type (▪, 5 mice), Bcl-2 transgenic wild-type (□, 5 mice), Vav-deficient (▾, 7 mice), and Bcl-2 transgenic Vav-deficient (▿, 8 mice). Cell numbers were calculated using the regions illustrated in Figure 5. Horizontal bars indicate the mean for each group of observations. Statistical analysis was performed using ANOVA. The hypothesis of normal distribution was confirmed for all the samples using the Kolmogorov-Smirnov test. ^*P < .05; ^**P < .01; ^***P < .001. n.s. indicates not significant.