Figure 3.
In vitro migratory and tubule-forming capacity of CD14+/VEGFR-2+ and CD14+/VEGFR-2- cells. (A) In a migration assay in the absence and presence of 50 ng/mL concentration of VEGF and 300 ng/mL MCP-1, a significantly higher number of CD14+/VEGFR-2+ cells (•) than CD14+/VEGFR-2- (○) cells migrated toward VEGF and MCP-1. (B) The CD14+/VEGFR-2+ cell population produced higher levels of the angiogenic growth factors, VEGF, G-CSF, and GM-CSF than the CD14+/VEGFR-2- population. (C) CD14+/VEGFR-2+ but not CD14+/VEGFR-2- cells formed capillarylike tubules in Matrigel. HAECs were used as control cells.