Suppression by GAD TMr-treated apoptosis-resistant high-avidity T-cells is Ag-nonspecific and is effective at different suppressor-responder ratios. HA-specific responder T cells and control or GAD TMr-treated Ann-V^- high-avidity T cells were cultured on HA/GAD-pulsed DCs either alone (▦, □, and ▪, respectively) or mixed together as indicated ( and ▧ at different ratios, maintaining the number of HA-specific responders constant. P values for the indicated comparisons are shown, as calculated by 2-tailed Student t test. Data are mean ± SE.