CXCL13 induces shear-resistant B-cell adhesion to ICAM-1 under flow conditions. (A) Shear-resistant B-cell adhesion to ICAM-1 alone or to ICAM-1 with CXCL13. The B cells that remained adherent at each shear-stress level were counted and expressed as a percentage of the initially bound B cells. (B) Pretreatment of B cells with PTX. The shear-resistant B-cell adhesion induced by CXCL13 (16 dyne/cm²) was abrogated by PTX. Data represent the mean ± SD of 3 independent experiments. *P < .01 compared with vehicle-treated B cells.