Patient no. 2 FIX ELISA and mean thrombin generation AUC. There is a sustained increase in the FIX:Ag throughout the study period that returns to baseline by the day-10 sample. This correlates with a sustained increase in the mean thrombin AUC that is seen throughout the study period as well. There was no change seen in the aPTT or the FIX:C level in this patient (not shown). Error bars indicate SEM.