Relationship between p-Shp2 levels and bone marrow cellularity in leukemia. For each sample, 20 μg cellular proteins was analyzed by Western blot with anti-Shp2 and β-actin antibodies. Results were expressed as Shp2/β-actin ratios, and the mean values in hypercellular leukemia and nonhypercellular leukemia cases were 1.873 ± 0.527 and 0.525 ± 0.262, respectively.