Figure 4.
Figure 4. Infiltration of WT and CCR5-/- Tregs, measured by quantitation of eGFP+CD4+ cell infiltrates in lymphoid tissues and target organs on day 5 after transplantation. Lethally conditioned B6D2 mice received transplants containing WT TCD-BM and WT whole splenic T cells, with FACS-sorted WT/eGFP (▪) or CCR5-/-/eGFP (▨) Tregs added. The numbers of eGFP+CD4+ cells infiltrating the organs shown were determined by flow cytometry on day 5 after transplantation. n = 4 mice/group. Data represent mean ± SEM.

Infiltration of WT and CCR5-/- Tregs, measured by quantitation of eGFP+CD4+ cell infiltrates in lymphoid tissues and target organs on day 5 after transplantation. Lethally conditioned B6D2 mice received transplants containing WT TCD-BM and WT whole splenic T cells, with FACS-sorted WT/eGFP (▪) or CCR5-/-/eGFP (▨) Tregs added. The numbers of eGFP+CD4+ cells infiltrating the organs shown were determined by flow cytometry on day 5 after transplantation. n = 4 mice/group. Data represent mean ± SEM.

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