Figure 2.
Dexamethasone fails to enhance ILT3 expression on DCs. Monocyte-derived human DCs were incubated for 48 hours with medium alone or medium containing 10 nM 1,25(OH)2D3, 10 ng/mL IL-10, or 100 nM dexamethasone, either when immature or during LPS-induced (100 ng/mL) maturation. Surface expression of ILT3 and CD83 molecules was determined by cytofluorimetry. Results are expressed as percent of the control geometric MFI. A representative experiment out of 2 performed is shown.