Effects of NGF deprivation on IL-10 production. IL-10 concentration was measured in conditioned media (n = 6) of LPS-treated monocytes incubated for 24 hours with anti-NGF antibody or with goat IgG as control. The neutralization of endogenous NGF using anti-NGF antibodies induced a significant decrease in IL-10 production when compared with IgG treatment (^**P < .01 according to the Tukey-Kramer test).