The uptake of exogenous GSH by activated T cells. (A) Activated T cells (deprived of IL-2) were incubated for 5 days either alone, with acivicin (5 mmol/L) or GSH (3 mmol/L), or with acivicin and GSH together. Values are means ± SEM of triplicate cultures, and the results are representative of four independent experiments. (B) Activated T cells incubated alone, with IL-2 (5 ng/mL) or with GSH (3 mmol/L) for 2 days were assessed for their total GSH content (expressed as nmol/10⁶ cells; see Materials and Methods). The initial GSH content, at day 0, was also determined. Values represent means ± SEM for three independent experiments.