Fig. 1.
E64d blocks the upregulation of Fas ligand mRNA induced by anti-CD3 antibody. 2B4.11 cells (106 cells/mL) were stimulated in 60-mm tissue culture dishes coated with 2C11 (20 μg/dish) for 4 hours in the presence or absence of 100 μmol/L E64d. Total RNA was extracted from the cells and Northern blot analysis performed.
