Comparison of peripheral blood counts. Values representing the mean ± SD (indicated by error bars) of total white blood cell counts, hemoglobin content, and total platelet counts are shown for nontransgenic or hCG–PML-RARα transgenic mice with nonleukemic or leukemic phenotypes. Statistically significant differences were observed for the percentage of mature myeloid cells in nontransgenic mice versus hCG–PML-RARα (nonleukemic and leukemic) mice (P < .001), the decrease in hemoglobin for hCG–PML-RARα (leukemic) mice (P < .001), and the decrease in platelet counts for hCG–PML-RARα (leukemic) mice (P < .01).