Fig. 3.
Fig. 3. Inhibition by neutralizing anti–IL-3 and anti–IFN-γ antibody of IL-6– and TNF-α–induced mast cell development. Mouse spleen cells were cultured with rIL-6 and rTNF-α in the presence or absence of neutralizing anti–IL-3 or anti–IFN-γ antibody (3 μg/mL). Mast cell number (A) and histamine quantity (B) per culture were determined on day 12. * P < .01 compared with data without antibody.

Inhibition by neutralizing anti–IL-3 and anti–IFN-γ antibody of IL-6– and TNF-α–induced mast cell development. Mouse spleen cells were cultured with rIL-6 and rTNF-α in the presence or absence of neutralizing anti–IL-3 or anti–IFN-γ antibody (3 μg/mL). Mast cell number (A) and histamine quantity (B) per culture were determined on day 12. * P < .01 compared with data without antibody.

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