Comparison of engraftment in gender-matched and mismatched transplants. To compare engraftment in the gender-matched (▪) and mismatched (▴) transplants, ASM activities were determined. For this comparison, the transplants were performed on 1-day old ASMKO animals subjected to 200 cGy of radiation before the transplant, and receiving 3 × 107 normal cells/g of body weight. 1 U = the amount of BODIPY-ceramide produced/hour/mL. The mean and standard error of the mean are plotted in the graph. Note that although the mean values are higher for gender-matched transplants as compared with gender-mismatched, the differences are not statistically significant. The t-test values for months 1, 2, and 3 were t = 1.84/P = .079, t = 0.847/P = .415, and t = 1.13/P = .272, respectively.
