Fig. 4.
CD19+ B-cell development from CD34+CD19− input cell populations in NOD/SCID recipients. Elimination of contaminating CD19+ cells by FACS from input CD34 cell fractions had no effect on the generation of B-cell precursors in the mice. The histograms show that, as in other experiments, output cells expressing CD19 predominated in the BM, spleen, and PB of repopulated mice.