Fig. 2.
Bcl-2 downmodulated lymphocyte population is undergoing apoptosis. The Bcl-2 expression of cells in CD4XL-PBMC was analyzed on day 3. (A) Based on the light scatter profiles, the low FSC/high SSC Apo Fr. was compared with high FSC/low SSC Int Fr. Histograms of Bcl-2 in the total lymphocyte fraction [box 3 (medium), box 4 (CD4XL)], and after CD4XL in Apo Fr. (box 5) and Int Fr. (box 6) are indicated. (B) Comparison of the MFI level of Bcl-2 between the apoptotic and intact lymphocyte fractions (n = 9). Values of statistical significance determined by paired t test are indicated.