Quantitation and specificity of liposome binding to SMS-SB and other B-lymphoid cell lines. Aliquots of SMS-SB (A), RPMI-8226 (B), and Raji cells (C) were mixed with either CD23-containing (solid line) or glycophorin-containing (broken line) fluorescent liposomes, washed and analyzed by flow cytometry for liposome binding. (D) Illustrates the binding data for SMS-SB and RPMI-8226 cells exposed to CD23-containing liposomes, which had been preincubated for 1 hour with 10 μg of EBVCS4 or MoAb25 anti-CD23 MoAbs before addition to the cells; the autofluorescence pattern of each cell is illustrated as a broken line.