Fig. 1.
![Fig. 1. Human MM cells grow in fetal human bone implants within SCID-hu mice. SCID-hu mice were treated with irradiation (400 cGy), injected directly into the marrow cavity of the left fetal human bone implant with 5 × 104 ARH-77 MM cells or with PBS, and killed 12 weeks later. H&E-stained tissue sections of the left human fetal bone marrow implant from SCID-hu mice injected with ARH-77 MM cells (original magnification × 100 [A]) or PBS (original magnification × 40 [B]) are shown. / Immunoperoxidase staining of the same human fetal bone marrow implant from SCID-hu mice injected with ARH-77 MM cells was also performed using antihuman κ (original magnification × 100 [C]) and antihuman λ (original magnification × 100 [D]) Ig light chain Abs.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/90/2/10.1182_blood.v90.2.754/4/bl_0023f1b.jpeg?Expires=1735503802&Signature=ynCVzsWoLgDJOj~7~sZM1xLpg4IHN~jJo5aThf2nUS5unbUVRFQpN-lUQcTcAtcUprvLYH9fMcACv3ZUdrKv5meRVWeJ-RF7Ik8J3NT4ZE~TEmBxMVRqpOqstmAZ22A26Krweaf8pyp44~UZ7iMCtjhp5VD~S8D384gdB-1yRzO1bd3MgLg~RWV1TWxKImKuvA1ggon1SZqFpVaAdHiLadgenNBSemUniOMJQL6I1QNwHNrj3ZwBxiPweQ~bzdvqboB4X6hn5EIfh8iQcQ4o8yxmkXn4Kq4fkDzLqMQrjCD-4UaHaoHNJonUvSG~TMRhS2uTZTZbKvsIUIbLZzLbtg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Human MM cells grow in fetal human bone implants within SCID-hu mice. SCID-hu mice were treated with irradiation (400 cGy), injected directly into the marrow cavity of the left fetal human bone implant with 5 × 104 ARH-77 MM cells or with PBS, and killed 12 weeks later. H&E-stained tissue sections of the left human fetal bone marrow implant from SCID-hu mice injected with ARH-77 MM cells (original magnification × 100 [A]) or PBS (original magnification × 40 [B]) are shown.
Immunoperoxidase staining of the same human fetal bone marrow implant from SCID-hu mice injected with ARH-77 MM cells was also performed using antihuman κ (original magnification × 100 [C]) and antihuman λ (original magnification × 100 [D]) Ig light chain Abs.
