Fig. 3.
![Fig. 3. Metastasis of MM cells within SCID-hu mice. SCID-hu mice were treated with irradiation (400 cGy), injected directly into the marrow cavity of the left fetal human bone implant with 5 × 104 ARH-77 MM cells, and killed 12 weeks later. H&E (original magnification × 100 [A] and × 400 [B]) and immunoperoxidase staining with anti-κ Ig Ab (original magnification × 100 [C] and × 1,000 [D]) of the right-sided human fetal bone marrow implant is shown. / Mediastinum (original magnification × 40 [E]) and murine vertebral BM (original magnification × 400 [F ]) were also stained with H&E.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/90/2/10.1182_blood.v90.2.754/4/bl_0023f3b.jpeg?Expires=1735505699&Signature=MoRHApREApzbZ6cQq5KOjR~Cct~civfYlU~~JuVEFd9JK24JJdzrCp16QPMLRX5pVw-69Pjp1PSZwwTYYjcNlqo7ZLB7~lWn5k5OmkCTGA2Zivtx9w7INVlL--yNABwAB1JfOBQxYcRRw~UKa6QnEoeRW-jrHExlrpI6h~d104qU2lNeBGOYM-3mS-FwZqvZfN5v-xzBsdOEjbG1nmFFS7~EUwrhl9vzet2clNMf~BIeJ2Ibt1GsluAnO~vh5JXSIR3QC4G~KPp3-Ed0D4gs~iXQdVvekKnsNZFBGi28OjSzqDGK9RjTJss2~cr8cGEGTEnJqV2IX0lDI-0pT7JV6A__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Metastasis of MM cells within SCID-hu mice. SCID-hu mice were treated with irradiation (400 cGy), injected directly into the marrow cavity of the left fetal human bone implant with 5 × 104 ARH-77 MM cells, and killed 12 weeks later. H&E (original magnification × 100 [A] and × 400 [B]) and immunoperoxidase staining with anti-κ Ig Ab (original magnification × 100 [C] and × 1,000 [D]) of the right-sided human fetal bone marrow implant is shown.
Mediastinum (original magnification × 40 [E]) and murine vertebral BM (original magnification × 400 [F ]) were also stained with H&E.
