Fig. 6.
Growth of human MM cells within SCID-hu mice triggers monoclonal Ig light chain renal tubular staining. U-266 MM cells (5 × 104) were injected directly into the marrow cavity of the left human fetal bone implant in SCID-hu mice. Mice were killed 12 weeks later and renal tissue was stained with rabbit antihuman λ (original magnification × 100 [A]) and κ (original magnification × 100 [B]) immunoperoxidase Abs.