Phylogenic analysis of HCC-4 and alignment with HCC-1. (A) Phylogenic analysis of the relationship of HCC-4 to other human CC chemokines is shown. HCC-3 (GenBank accession no. Z70293) is a potential splice variant of HCC-1. MIP-3 (GenBank accession no. P55773) is a potential splice variant of MPIF-1. (B) CLUSTAL alignment of HCC-4 and HCC-1. Similar amino acid residues are boxed, whereas identities are boxed and shaded.