Histopathological examination. Induction of lethal acute GVHD and administration of anti-FasL and/or anti-TNFα MoAb were performed as described in Fig 1. On day 19 for the GVHD group or day 21 for the other groups, 3 mice in each group were killed. Paraffin section of the liver (A through E), intestine (F through J), skin (K through O), and spleen (P through T) were stained by hematoxylin and eosin. Sections from age-matched normal CBF1 are also represented. The specimens shown are representatives of 3 mice in each group with similar histology. Original magnification × 100.