Hypothetical scheme of myeloid differentiation. The expression of NAMLAA is indicated for each differentiation stage with + and −. The bars represent the various types of leukemias and non-Hodgkin's lymphomas and indicate where these malignancies can be located according to their maturation arrest. To indicate the heterogeneous phenotype found in most AML patients, the bars fade into each other. CML, chronic myeloid leukemia; NHL, non-Hodgkin's lymphoma.