Fig. 4.
Upregulation of CD44 isoforms by bFGF. Cultured HUVEC were treated with 10 ng/mL bFGF for several time periods. Isoforms are stained for FACS-analysis by the identified antibodies. Mean fluorescence intensity (MFI) of five independent experiments (± SEM) is given as the percentage of untreated cells cultured for the same time without bFGF. The absolute levels of expression (MFI ± SEM) were 185 ± 45, 44 ± 8, 13 ± 2 (negative), 8 ± 2 (negative), 26 ± 5 for CD44s and CD44 exon v5, v6, v7, and v10, respectively (conjugate control 8 ± 1).