American Society of Hematology

Fig. 4.

$Fig. 4. Fraction of interacting adult (A) and neonatal (B) neutrophils that rolled on CHO-P-selectin after a 2-minute stationary contact period with increasing shear stress. Neutrophils were left untreated (•) or were preincubated with anti-CD11a MoAb, R7.1 (10 μg/mL; ▾), anti-CD18, R15.7 (10 μg/mL; ▴), or anti–L-selectin, DREG 56 (50 μg/mL; ▪). Data are expressed as the mean rolling fraction ± SEM from 7 to 14 experiments. *P < .005 compared with control neutrophils. +P < .05 compared with control. **P < .02 versus anti-CD11a–treated neutrophils.$

Fraction of interacting adult (A) and neonatal (B) neutrophils that rolled on CHO-P-selectin after a 2-minute stationary contact period with increasing shear stress. Neutrophils were left untreated (•) or were preincubated with anti-CD11a MoAb, R7.1 (10 μg/mL; ▾), anti-CD18, R15.7 (10 μg/mL; ▴), or anti–L-selectin, DREG 56 (50 μg/mL; ▪). Data are expressed as the mean rolling fraction ± SEM from 7 to 14 experiments. *P < .005 compared with control neutrophils. +P < .05 compared with control. **P < .02 versus anti-CD11a–treated neutrophils.

This Feature Is Available To Subscribers Only