Fig. 6.
Fig. 6. Immunofluorescence staining of human F.IX expressed in hepatocytes 22 weeks after injection of AAV-CMV-F.IX (A) or AAV-EF1α-F.IX (B and C) into portal vein of adult C57BL/6 mice. The dose injected in the mouse used for liver sections (B) and (C) was 2.1 × 1010 vector genomes. Plasma levels of hF.IX were 120 ng/mL at the time this mouse was killed. Original magnification × 200.

Immunofluorescence staining of human F.IX expressed in hepatocytes 22 weeks after injection of AAV-CMV-F.IX (A) or AAV-EF1α-F.IX (B and C) into portal vein of adult C57BL/6 mice. The dose injected in the mouse used for liver sections (B) and (C) was 2.1 × 1010 vector genomes. Plasma levels of hF.IX were 120 ng/mL at the time this mouse was killed. Original magnification × 200.

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