Fig. 2.
Partial CGH karyotypes (left) and corresponding ratio profiles (right) observed in cases no. MM18 and MM26. Case no. MM18 showed deletions of chromosomes 6q21 and 13q14-22 and gains of 9q and chromosome 15. Case no. MM26 showed gain of 11q and loss of 16q. Hybridized tumor DNA was visualized via fluorescein isothiocyanate (green) and control DNA was visualized via Texas Red (red). The averaged green to red fluorescent signal ratio along the length of the chromosome is shown. The blue line in the ratio profile represents the mean of 8 to 10 chromosomes and the yellow line represents the standard deviation. The vertical red and green bars on the right of the ideogram indicate threshold values of 0.8 and 1.20 for loss and gain, respectively.