Comparison of eosinophil recruitment and EPO levels in ICAM-1–deficient and wild-type mice. Ragweed-sensitized mice (ICAM-1–deficient or control wild-type mice; n = 10 mice; 3 separate experiments) were challenged with an intraperitoneal injection of ragweed allergen. Forty-eight hours later, the percentage of transmigrated peritoneal eosinophils (A) and EPO levels (B) were assessed. ICAM-1–deficient mice developed significantly less peritoneal eosinophilia (P = .03) and lower EPO levels (P = .05) compared with control wild-type mice after allergen.