Fig. 3.
![Fig. 3. Effect of FVII(a)-immunodepleted ACSET [A(ID)] on VEGF production. Confluent fibroblasts were incubated for 24 hours in the presence of 100 nmol/L FVII(a) or immunodepleted ACSET [A(ID)] used at the same protein concentration as FVII(a). Secreted VEGF was assessed by a specific ELISA. Results are expressed as the fold induction of VEGF production, with VEGF secretion by unstimulated fibroblasts (NS) being considered as onefold induction and corresponding to 109.4 ± 14.6 pg/mL of secreted VEGF. Each point represents the mean ± SEM of at least eight different determinations each performed in triplicate. *P < .01 versus unstimulated and A(ID)-stimulated fibroblasts.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/91/8/10.1182_blood.v91.8.2698.2698_2698_2703/5/blod40855003x.jpeg?Expires=1735826254&Signature=uwVlqlC4nRaAqqvZMRbnzBP2TmxJuZ~jDwrq5jrCidIPrRN4X~YYH7bXRW2Axoe5l5VBuOc86Y-3DlfwKdQnDofxw-pjbjlQ7wiUr0ZuevD0rDSFQgt0CrtKOlrkBGytf~iBJJtIwwIJO8ep3NQGn4iuGKwk~0gPScALX06UQvd4x8qwH9lMPHdJOZ5~JYrnLpb0ZxTAuLcextX5~QJ5qNOwM1QNboe18v8CUXn-b5xvx6MZUEw5mrF-oZgh1S9VOc-hO46BIbB7IVIn-a7VArjoj53JSe3bBQRH4Smn1hDEJRB2NkSaj9V~15SXlyN52YFK8M3hf99fmXN2tnFl9w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effect of FVII(a)-immunodepleted ACSET [A(ID)] on VEGF production. Confluent fibroblasts were incubated for 24 hours in the presence of 100 nmol/L FVII(a) or immunodepleted ACSET [A(ID)] used at the same protein concentration as FVII(a). Secreted VEGF was assessed by a specific ELISA. Results are expressed as the fold induction of VEGF production, with VEGF secretion by unstimulated fibroblasts (NS) being considered as onefold induction and corresponding to 109.4 ± 14.6 pg/mL of secreted VEGF. Each point represents the mean ± SEM of at least eight different determinations each performed in triplicate. *P < .01 versus unstimulated and A(ID)-stimulated fibroblasts.
