Fig. 2.
M-CSF secretion is decreased by different RA metabolites in MO but not in MO-derived MAC. Either MO or MO-derived MAC were cultured for 48 hours with or without serum plus 10−7mol/L 9-cis-RA, all-trans-RA, 13-cis-RA, or retinol on petri dishes. The M-CSF content of these supernatants was analyzed by ELISA.