Fig. 1.
Effect of gallium nitrate on the growth of gallium-sensitive (S) and -resistant (R1 and R2) CCRF-CEM cells. Cells were plated at 2 × 105 cells/mL in the presence of increasing concentrations of gallium nitrate, and growth was determined by MTT assay after a 72-hour incubation. (A) gallium-resistant cells (•) that had been maintained continuously in medium containing 150 μmol/L gallium nitrate (R1 cells). (B) gallium-resistant cells (•) that had been grown without gallium in the medium for 10 weeks (R2 cells). (○) gallium-sensitive cells.