Fig. 7.
Concentration of blood murine and human Ig in SCID mice receiving XG-2 cells and anti-gp130 MoAbs. Three mice were injected IP with 50 × 106 XG-2 cells and B1 +I2 anti-gp130 MoAbs. Peripheral blood was harvested 2, 4, 6, 8, 10, and 14 weeks after XG-2-cell inoculation and the concentrations of human Ig, human sIL-6R, and human sgp130 were determined by ELISA. The limit of sensitivity of the ELISA was 1 μg/mL for human Ig, 20 ng/mL for human sIL-6R, and 5 ng/mL for human sgp130. Results are the mean ± SD of the determinations. For some points, the error bars were too small to be visible on the graphs.
