Fig. 6.
![Fig. 6. Displacement curves of125I-[Ac-His-1]-PACAP(1-27) to tissue sections of a human thymus (A) and a human lymph node (B). Tissue sections are incubated with 15,000 cpm/100 μL radioligand and increasing concentrations of PACAP(1-27) (▴) and VIP (▪), or somatostatin (SS-14) (•) at a concentration of 100 nmol/L. Nonspecific binding was subtracted from all values. In all cases, complete displacement of the ligand is achieved by VIP and PACAP. SS-14 was inactive in the nanomolar range.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/92/1/10.1182_blood.v92.1.191.413k12_191_197/5/blod41312006x.jpeg?Expires=1735555721&Signature=mf3vzGVu~sPEsHEawuERTnVuWkO3z6-UlE27qJ1LRoeXWPhEYg4P9bnGN~vjeXt72bW9YbbLd8pO-uPhcupz4PBG3eQ-zVxIlE~AMJWFaHyMd3m5Guzk1Gzp0rbBrqBbVDRYwI~Boydq~9VhlYeg~i2Qlb0tKJPbEWOMXH1JcIMrIplmGpUUdoFboUZq1uOUD04InfA~0jucIl195o~oCtAkg7uYDR0GN6j1gfw68OGOST32YkdyG~CGMSMcPtdbaB3gVs0wQQKzYdz74U6Xtnf4NboXH20Ip3ibzLv5A3fpdSn5ou3y0oZpZkaT7XqwUIMZIkcgi5BF-Tfqm7ZK6Q__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Displacement curves of125I-[Ac-His-1]-PACAP(1-27) to tissue sections of a human thymus (A) and a human lymph node (B). Tissue sections are incubated with 15,000 cpm/100 μL radioligand and increasing concentrations of PACAP(1-27) (▴) and VIP (▪), or somatostatin (SS-14) (•) at a concentration of 100 nmol/L. Nonspecific binding was subtracted from all values. In all cases, complete displacement of the ligand is achieved by VIP and PACAP. SS-14 was inactive in the nanomolar range.
