Partial CGH karyotypes (left) and corresponding ratio profiles (right) illustrating high level amplification of chromosomal regions in DLBL tumors studied. Hybridized tumor DNA was visualized via FITC (green) and control DNA via Texas Red (red). The averaged green to red fluorescent signal ratio along the length of the chromosome is shown. The blue line in the ratio profile represents the mean of eight to 10 chromosomes and the yellow line represents the standard deviation. The vertical red and green bars on the right of the ideogram indicate threshold values of 0.80 and 1.20 for loss and gain, respectively.