Fig. 1.
Fig. 1. CD8αβ expression on PBL from HIV-1 seronegative and HIV-1 seropositive individuals. (A) The linear regression analysis of CD8αβ MF and absolute CD4+T-lymphocyte counts from data obtained from 21 HIV-1 seronegative individuals showed no significant deviation from a slope of 0. (B) The linear regression analysis of CD8αβ MF and absolute CD4+ T-lymphocyte counts from data obtained from 103 HIV-1 seropositive individuals showed a significant deviation from a slope of 0 (P < .01). (C) CD8αβ MF on PBL from 21 HIV-1 seronegative individuals, 58 HIV-1 seropositive individuals (> 200 CD4+ T lymphocytes/μL), and 45 HIV-1 seropositive individuals (< 200 CD4+ T lymphocytes/μL). Significant differences were observed between all three groups (HIV-1 seronegative v either HIV-1 seropositive patient group:P < .0001; between HIV-1 seropositive patient groups:P < .01).

CD8αβ expression on PBL from HIV-1 seronegative and HIV-1 seropositive individuals. (A) The linear regression analysis of CD8αβ MF and absolute CD4+T-lymphocyte counts from data obtained from 21 HIV-1 seronegative individuals showed no significant deviation from a slope of 0. (B) The linear regression analysis of CD8αβ MF and absolute CD4+ T-lymphocyte counts from data obtained from 103 HIV-1 seropositive individuals showed a significant deviation from a slope of 0 (P < .01). (C) CD8αβ MF on PBL from 21 HIV-1 seronegative individuals, 58 HIV-1 seropositive individuals (> 200 CD4+ T lymphocytes/μL), and 45 HIV-1 seropositive individuals (< 200 CD4+ T lymphocytes/μL). Significant differences were observed between all three groups (HIV-1 seronegative v either HIV-1 seropositive patient group:P < .0001; between HIV-1 seropositive patient groups:P < .01).

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