In vitro DNaseI footprint analysis of the 5′HS1 core element. (A) Footprint of the 5′HS1 sense strand probe showing footprints A-C, D1-D3, and E-G. Hypersensitive bases indicated by arrows. (B-C). Footprint of 5′HS1 antisense strand probe protected by the indicated MEL or Jurkat cell nuclear extract. G, chemical sequencing G ladder of the same probe; N, no extract. {/ANNT;;4224n;36608n;0n}B {/ANNT;4224n;;103488n;0n}C {/ANNT;4224n;;0n;0n}A